| 2023-07 |
Massively parallel evaluation and computational prediction of the activities and specificities of 17 small Cas9s |
Nature Methods
|
| 2023-05 |
Deep learning models to predict the editing efficiencies and outcomes of diverse base editors |
Nature Biotechnology
|
| 2023-05 |
In vivo application of base and prime editing to treat inherited retinal diseases |
PROGRESS IN RETINAL AND EYE RESEARCH
|
| 2023-05 |
Prediction of efficiencies for diverse prime editing systems in multiple cell types |
Cell
|
| 2023-03 |
Sniper2L is a high-fidelity Cas9 variant with high activity |
Nature Chemical Biology
|
| 2022-09 |
Magnetogenetics with Piezo1 Mechanosensitive Ion Channel for CRISPR Gene Editing |
Nano Letters
|
| 2022-06 |
High-throughput functional evaluation of human cancer-associated mutations using base editors |
NATURE BIOTECHNOLOGY
|
| 2022-03 |
Generation of mutation-corrected induced pluripotent stem cell lines derived from adrenoleukodystrophy patient by using homology directed repair |
STEM CELL RESEARCH
|
| 2022-02 |
Basic Principles and Clinical Applications of CRISPR-Based Genome Editing |
YONSEI MEDICAL JOURNAL
|
| 2022-02 |
In vivo outer hair cell gene editing ameliorates progressive hearing loss in dominant-negative Kcnq4 murine model |
THERANOSTICS
|
| 2022-02 |
Application of prime editing to the correction of mutations and phenotypes in adult mice with liver and eye diseases |
Nature Biomedical Engineering
|
| 2021-12 |
Improving CRISPR tools by elucidating DNA repair |
NATURE BIOTECHNOLOGY
|
| 2021-09 |
Generation of a more efficient prime editor 2 by addition of the Rad51 DNA-binding domain |
NATURE COMMUNICATIONS
|
| 2021-02 |
Recording of elapsed time and temporal information about biological events using Cas9 |
CELL
|
| 2021-02 |
Predicting the efficiency of prime editing guide RNAs in human cells |
NATURE BIOTECHNOLOGY
|
| 2021-01 |
An autophagy enhancer ameliorates diabetes of human IAPP-transgenic mice through clearance of amyloidogenic oligomer |
NATURE COMMUNICATIONS
|
| 2020-11 |
Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer |
CELL DEATH AND DIFFERENTIATION
|
| 2020-11 |
Prediction of the sequence-specific cleavage activity of Cas9 variants |
NATURE BIOTECHNOLOGY
|
| 2020-09 |
Sequence-specific prediction of the efficiencies of adenine and cytosine base editors |
NATURE BIOTECHNOLOGY
|
| 2020-07 |
Chemical Controllable Gene Drive in Drosophila |
ACS SYNTHETIC BIOLOGY
|
| 2020-01 |
High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells |
Nature biomedical engineering
|
| 2019-11 |
SpCas9 activity prediction by DeepSpCas9, a deep learning – based model with high generalization performance |
SCIENCE ADVANCES
|
| 2019-09 |
Programmable Nuclease-Based Integration into Novel Extragenic Genomic Safe Harbor Identified from Korean Population-Based CNV Analysis. |
Molecular therapy oncolytics.
|
| 2019-06 |
Therapeutic application of the CRISPR system: current issues and new prospects |
HUMAN GENETICS
|
| 2019-05 |
En bloc and segmental deletions of human XIST reveal X chromosome inactivation-involving RNA elements |
NUCLEIC ACIDS RESEARCH
|
| 2018-07 |
In vivo gene correction with targeted sequence substitution through microhomology-mediated end joining |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2018-07 |
Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination |
NEURON
|
| 2018-07 |
Paired D10A Cas9 nickases are sometimes more efficient than individual nucleases for gene disruption |
NUCLEIC ACIDS RESEARCH
|
| 2018-03 |
Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth |
GENOME RESEARCH
|
| 2018-03 |
Deep learning improves prediction of CRISPR–Cpf1 guide RNA activity |
NATURE BIOTECHNOLOGY
|
| 2017-12 |
RanBPM: a potential therapeutic target for modulating diverse physiological disorders. |
DRUG DISCOVERY TODAY
|
| 2017-06 |
Contriction of the mitochondrial inner compartment is a priming event for mitochondrial division |
NATURE COMMUNICATIONS
|
| 2017-03 |
Targeted Genome Engineering to Control VEGF Expression in Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells: Potential Implications for the Treatment of Myocardial Infarction. |
STEM CELLS TRANSLATIONAL MEDICINE
|
| 2017-03 |
Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia |
AMERICAN JOURNAL OF HUMAN GENETICS
|
| 2017-02 |
In vivo high-throughput profiling of CRISPR-Cpf1 activity. |
NATURE METHODS
|
| 2017-01 |
Concise Review: Fate Determination of Stem Cells by Deubiquitinating Enzymes |
STEM CELLS
|
| 2017-01 |
Cell-Penetrating Peptide-Mediated Delivery of Cas9 Protein and Guide RNA for Genome Editing. |
Methods in molecular biology (Clifton, N.J.)
|
| 2016-12 |
Generation of Delta F508-CFTR T84 cell lines by CRISPR/Cas9-mediated genome editing |
BIOTECHNOLOGY LETTERS
|
| 2016-12 |
Environmental enrichment enhances synaptic plasticity by internalization of striatal dopamine transporters |
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
|
| 2016-11 |
Elucidation of Relevant Neuroinflammation Mechanisms Using Gene Expression Profiling in Patients with Amyotrophic Lateral Sclerosis |
PLOS ONE
|
| 2016-09 |
Heroes of peer review: Hyongbum (Henry) Kim |
GENOME BIOLOGY
|
| 2016-09 |
Astroglial Activation by an Enriched Environment after Transplantation of Mesenchymal Stem Cells Enhances Angiogenesis after Hypoxic-Ischemic Brain Injury |
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
|
| 2016-08 |
Regulation of pluripotency and differentiation by deubiquitinating enzymes. |
CELL DEATH AND DIFFERENTIATION
|
| 2016-07 |
In Situ Pluripotency Factor Expression Promotes Functional Recovery From Cerebral Ischemia |
MOLECULAR THERAPY
|
| 2016-02 |
Deficiency in DGCR8-dependent canonical microRNAs causes infertility due to multiple abnormalities during uterine development in mice |
SCIENTIFIC REPORTS
|
| 2016-02 |
Designed nucleases for targeted genome editing |
PLANT BIOTECHNOLOGY JOURNAL
|
| 2015-12 |
CRISPR/Cas9 system as an innovative genetic engineering tool:Enhancements in sequence specificity and delivery methods |
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
|
| 2015-08 |
Diabetic Mesenchymal Stem Cells Are Ineffective for Improving Limb Ischemia Due to Their Impaired Angiogenic Capability |
CELL TRANSPLANTATION
|
| 2015-06 |
Recent developments and clinical studies utilizing engineered zinc finger nuclease technology |
CELLULAR AND MOLECULAR LIFE SCIENCES
|
| 2015-06 |
Rh D blood group conversion using transcription activator-like effector nucleases |
NATURE COMMUNICATIONS
|
| 2015-05 |
Effective Gene Delivery into Human Stem Cells with a Cell-Targeting Peptide-Modified Bioreducible Polymer |
SMALL
|
| 2014-08 |
Doxycycline Enhances Survival and Self-Renewal of Human Pluripotent Stem Cells |
STEM CELL REPORTS
|
| 2014-08 |
Hepatitis C Virus Entry Is Impaired by Claudin-1 Downregulation in Diacylglycerol Acyltransferase-1-Deficient Cells |
JOURNAL OF VIROLOGY
|
| 2014-06 |
Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA |
GENOME RESEARCH
|