| 2024-02 |
Deficiency of circadian clock gene Bmal1 exacerbates noncanonical inflammasome-mediated pyroptosis and lethality via Rev-erbα-C/EBPβ-SAA1 axis |
Experimental & Molecular Medicine
|
| 2023-06 |
Extracellular Acidification Augments NLRP3-Mediated Inflammasome Signaling in Macrophages |
Immune Network
|
| 2023-05 |
NLRP3 Exacerbate NETosis-Associated Neuroinflammation in an LPS-Induced Inflamed Brain |
Immune Network
|
| 2023-02 |
Distinctive role of inflammation in tissue repair and regeneration |
ARCHIVES OF PHARMACAL RESEARCH
|
| 2022-08 |
Therapeutic effect of NLRP3 inhibition on hearing loss induced by systemic inflammation in a CAPS-associated mouse model |
EBioMedicine
|
| 2022-06 |
Design and synthesis of an N-benzyl 5-(4-sulfamoylbenzylidene-2-thioxothiazolidin-4-one scaffold as a novel NLRP3 inflammasome inhibitor |
Bioorganic and Medicinal Chemistry Letters
|
| 2022-05 |
Differential Regional Vulnerability of the Brain to Mild Neuroinflammation Induced by Systemic LPS Treatment in Mice |
Journal of Inflammation Research
|
| 2022-04 |
Short Term Isocaloric Ketogenic Diet Modulates NLRP3 Inflammasome Via B-hydroxybutyrate and Fibroblast Growth Factor 21 |
FRONTIERS IN IMMUNOLOGY
|
| 2022-01 |
PGC-1α inhibits the NLRP3 inflammasome via preserving mitochondrial viability to protect kidney fibrosis |
CELL DEATH & DISEASE
|
| 2021-12 |
Intracellular NAD(+) Depletion Confers a Priming Signal for NLRP3 Inflammasome Activation |
FRONTIERS IN IMMUNOLOGY
|
| 2021-12 |
Antimicrobial Peptide LL-37 Drives Rosacea-Like Skin Inflammation in an NLRP3-Dependent Manner |
JOURNAL OF INVESTIGATIVE DERMATOLOGY
|
| 2021-09 |
Neutrophils facilitate prolonged inflammasome response in the DAMP-rich inflammatory milieu |
FRONTIERS IN IMMUNOLOGY
|
| 2021-05 |
Distinct Features of Brain-Resident Macrophages: Microglia and Non-Parenchymal Brain Macrophages |
MOLECULES AND CELLS
|
| 2021-04 |
SGK1 inhibition in glia ameliorates pathologies and symptoms in Parkinson disease animal models |
EMBO MOLECULAR MEDICINE
|
| 2020-12 |
Antiviral efficacy of orally delivered neoagarohexaose, a nonconventional TLR4 agonist, against norovirus infection in mice |
BIOMATERIALS
|
| 2020-11 |
Bacterial Outer Membrane Vesicle-Mediated Cytosolic Delivery of Flagellin Triggers Host NLRC4 Canonical Inflammasome Signaling |
FRONTIERS IN IMMUNOLOGY
|
| 2020-09 |
ATP-P2X7–Induced Inflammasome Activation Contributes to Melanocyte Death and CD8<sup>+</sup> T-Cell Trafficking to the Skin in Vitiligo |
JOURNAL OF INVESTIGATIVE DERMATOLOGY
|
| 2020-05 |
SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease |
NATURE COMMUNICATIONS
|
| 2020-01 |
Non-invasive in vivo imaging of caspase-1 activation enables rapid and spatiotemporal detection of acute and chronic inflammatory disorders |
BIOMATERIALS
|
| 2019-12 |
Zika Virus Impairs Host NLRP3-mediated Inflammasome Activation in an NS3-dependent Manner |
Immune Network
|
| 2019-08 |
Proteomics-based functional studies reveal that galectin-3 plays a protective role in the pathogenesis of intestinal Behcet's disease |
SCIENTIFIC REPORTS
|
| 2019-05 |
Chemotherapeutic Agent Paclitaxel Mediates Priming of NLRP3 Inflammasome Activation |
FRONTIERS IN IMMUNOLOGY
|
| 2019-03 |
Brefeldin A-sensitive ER-Golgi vesicle trafficking contributes to NLRP3-dependent caspase-1 activation |
FASEB JOURNAL
|
| 2019-02 |
MPTP-driven NLRP3 inflammasome activation in microglia plays a central role in dopaminergic neurodegeneration |
CELL DEATH AND DIFFERENTIATION
|
| 2018-03 |
Palmitate and minimally-modified low-density lipoprotein cooperatively promote inflammatory responses in macrophages. |
PLOS ONE
|
| 2018-01 |
Prolonged Exposure to Lipopolysaccharide Induces NLRP3-Independent Maturation and Secretion of Interleukin (IL)-1β in Macrophages |
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
|
| 2017-12 |
Advanced glycation end products impair NLRP3 inflammasome-mediated innate immune responses in macrophages |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2017-11 |
NLRP3 Inflammasome contributes to lipopolysaccharide-induced depressive-like behaviors via indoleamine 2,3-dioxygenase induction |
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
|
| 2017-03 |
Bacterial secretant from Pseudomonas aeruginosa Dampens inflammasome activation in a Quorum sensing-Dependent Manner |
FRONTIERS IN IMMUNOLOGY
|
| 2017-01 |
Immunomodulatory/anti-inflammatory effect of ZOE-based dental materials |
DENTAL MATERIALS
|
| 2016-11 |
Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance |
ARCHIVES OF PHARMACAL RESEARCH
|
| 2016-10 |
25-hydroxycholesterol contributes to cerebral inflammation of X-linked adrenoleukodystrophy through activation of the NLRP3 inflammasome |
NATURE COMMUNICATIONS
|
| 2016-08 |
Inflammasome activation by cell volume regulation and inflammation associated hyponatremia: A vicious cycle |
MEDICAL HYPOTHESES
|
| 2016-02 |
Dysbiosis-induced IL-33 contributes to impaired antiviral immunity in the genital mucosa |
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
|
| 2015-11 |
Histone deacetylase 6 negatively regulates NLRP3 inflammasome activation |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2015-11 |
Rotenone-induced impairment of mitochondrial electron transport chain confers a selective priming signal for NLRP3 inflammasome activation |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2015-10 |
Defective mitochondrial fission augments NLRP3 inflammasome activation |
SCIENTIFIC REPORTS
|
| 2015-07 |
Non-transcriptional regulation of NLRP3 inflammasome signaling by IL-4 |
IMMUNOLOGY AND CELL BIOLOGY
|
| 2013-10 |
The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity |
JOURNAL OF IMMUNOLOGY
|
| 2013-08 |
Cobalt Chloride-induced Hypoxia Ameliorates NLRP3-Mediated Caspase-1 Activation in Mixed Glial Cultures |
IMMUNE NETWORK
|
| 2013-05 |
Restoration of ASC expression sensitizes colorectal cancer cells to genotoxic stress-induced caspase-independent cell death |
CANCER LETTERS
|
| 2013-04 |
Ribotoxic stress through p38 mitogen-activated protein kinase activates in Vitro the human pyrin inflammasome |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2012-12 |
Salmonella Promotes ASC Oligomerization-dependent Caspase-1 Activation |
IMMUNE NETWORK
|
| 2011-09 |
Pyrin Domain (PYD)-containing Inflammasome in Innate Immunity |
Journal of Bacteriology and Virology
|
| 2011-07 |
TRADD is critical for resistance to TRAIL-induced cell death through NF-kappa B activation |
FEBS LETTERS
|
| 2010-08 |
CIIA Is a Novel Regulator of Detachment-Induced Cell Death |
Cancer Research
|
| 2010-06 |
Differential cytoprotective effect of copper- and iron-containing chlorophyllins against oxidative stress-mediated cell death |
Free Radical Research
|
| 2010-05 |
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis |
Nature Immunology
|
| 2010-03 |
Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome |
The Journal of biological chemistry
|
| 2009-03 |
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA |
Nature
|
| 2008-02 |
Mutations in NALP12 cause hereditary periodic fever syndromes |
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
|
| 2007-10 |
Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants |
MOLECULAR CELL
|
| 2007-09 |
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation |
CELL DEATH AND DIFFERENTIATION
|
| 2006-02 |
Cryopyrin and pyrin activate caspase-1, but not NF-kappa B, via ASC oligomerization |
CELL DEATH AND DIFFERENTIATION
|
| 2004-02 |
Inhibition of apoptosis signal-regulating kinase 1 by nitric oxide through a thiol redox mechanism |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2001-09 |
Iron chlorin e(6) scavenges hydroxyl radical and protects human endothelial cells against hydrogen peroxide toxicity |
BIOLOGICAL & PHARMACEUTICAL BULLETIN
|